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Submitted On:

October 16, 2025

Published On:

November 19, 2025

Updated On:

November 19, 2025

Correspondence:

Li Jiang, School of Stomatology, Jinan University, Guangzhou 510632, China

Citation

Jiang L. Antibacterial efficacy of nanocarrier-assisted antimicrobial photodynamic therapy (nano-apdt) against enterococcus faecalis in root canals: key findings and perspectives. J Dent Sci Oral Care. 2025;1(1):1–2.

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Antibacterial efficacy of nanocarrier-assisted antimicrobial photodynamic therapy (nanoapdt) against enterococcus faecalis in root canals: key findings and perspectives

Background
Persistent Enterococcus faecalis (E. faecalis) infection remains a primary cause of endodontic treatment failure due to its strong biofilm-forming ability, nutrient tolerance, and penetration into dentinal tubules and root canal isthmuses.1,2 Conventional irrigants such as sodium hypochlorite (NaOCl) remain the gold standard, exhibiting strong antibacterial and tissue-dissolving effects.3 However, high NaOCl concentrations are cytotoxic, reduce dentin microhardness, and risk periapical tissue injury, underscoring the need for safer and more biocompatible alternatives.4

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